Avandia News Archive

Avandia: Back from the Brink
-LawyersandSettlements.com
07/24/2008- As a result of events in 2007, Jack has been forced to face the prospect of early retirement, and must live a fairly stress-free life. In the Spring of that year he suffered a heart attack then heart failure, while he was taking Avandia. Could Avandia have contributed? More>>>

Doctor analyzes magazine's list of drugs to avoid
-KATU.Com
07/17/2008- Slickly produced ads for prescription drugs are everywhere, especially on TV, where they tout the latest pharmaceutical breakthroughs, usually accompanied by a long list of side effect warnings. More>>>

Avandia: Dead at 39
-Lawyers and Settlements

07/15/2008- Charles' wife had diabetes, and she had been taking Avandia as prescribed by her doctor. But it didn't do her any good. She died at the age of 39, after having experienced a series of heart problems and resulting surgeries. More>>>

FDA Updates Label for AVANDIA(R) to Include Clinical Findings Demonstrating Sustained Glycemic Control for Up to Five Years
-CNN

07/14/2008- GlaxoSmithKline announces today that the U.S. Food and Drug Administration (FDA) updated the prescribing information for AVANDIA(R) (rosiglitazone maleate) to include clinical findings from A Diabetes Outcome Progression Trial. More>>>

Should the FDA Require Cardiovascular Studies for Diabetes Medications?
-About.com

07/10/2008- The FDA is considering the possibility that required cardiovascular studies should be added to the approval process for diabetes drugs. There does seem to be a correlation between cardiovascular risks and diabetes medications. More>>>

Diabetes patients sue GSK: Lawsuit claims company suppressed data about diabetes drug's negative effects
-Lawyers and Settlements

07/08/2008- Two North Carolina patients have sued GlaxoSmithKline, claiming that the drug maker's diabetes pill, Avandia, caused their heart attacks. More>>>

Larger and Longer Trials Needed to Reduce Cardiac Risk in Diabetes Drugs

-FDA News
07/03/2008- Clinical trial designs for diabetes drugs are not good enough at detecting cardiovascular risk with GlaxoSmithKline’s (GSK) Avandia being Exhibit A, according to experts at a Tuesday meeting of CDER’s Endocrinologic and Metabolic Drugs Advisory Committee. More>>>

FDA Panel Calls for More Testing of Diabetes Drugs

-Forbes
07/01/2008- Drugs designed to control type 2 diabetes should be subjected to more thorough safety reviews to ensure they don't raise the risk of heart problems, U.S. Food and Drug Administration advisers said Wednesday. More>>>

Avandia: "This Medicine Is Deadly"

-Lawyers and Settlements
06/25/2008- Sam P. is happy to no longer be taking Avandia. He says he suffered severe side effects shortly after starting the medication, although he did not realize Avandia could have been causing his health problems. More>>>

Ketek, Avandia Among Drugs Doctors Won’t Take
-NewsInferno.com
06/23/2008- When doctors were recently asked which commonly prescribed medications they would avoid, they came up with the following eight. Perhaps you might want to reconsider these medications as well. At a minimum, speak to your doctor, as there are safer options for all of these medications. More>>>

Near Death Experience on Avandia

-Lawyers and Settlements
06/13/2008- Otis is a coach and teacher at a high school in Texas. He was put on Avandia for his diabetes approximately five years ago. In the fall of 2006 he was hospitalized for a heart attack, possibly an Avandia heart attack. At the time he was unaware of the problems with avandia--but that was about to change. More>>>

ADA: VA Trial Assertion on Rosiglitazone (Avandia) Heart Safety Called Problematic

-MedPage Today
06/11/2008- The VA Diabetes Trial analysis that showed no extra cardiovascular risk from rosiglitazone (Avandia) should not be taken as conclusive, cautioned independent investigators and statisticians. More>>>

Avandia: Sales of Diabetic Drug Gutted in Wake of Concern
-Lawyers and Settlements
06/06/2008- When the American Diabetes Association convenes here June 6th for their annual meeting, there is little doubt that amongst the topics up for discussion will be the fall of Avandia. More>>>

Six Years of Avandia and Two Heart Attacks Later
-Lawyers and Settlements
05/30/2008- March 1st, 2007 was a day Larry remembers well because he walked into hospital while having a heart attack--his second within 24 hours. He didn’t know he was having a heart attack, and it was the last thing he expected, because he had been taking Avandia for six years. More>>>

Diabetes drug to be limited over heart damage fears
-NewsScotsman.com
05/20/2008- The prescribing of a drug widely used to treat diabetes is to be restricted after warnings which linked it to heart problems. More>>>

Outgoing Glaxo Head Says Drugs Should be Tested Sooner, Better
-NewsInferno.com
05/20/2008- Outgoing head of GlaxoSmithKline (GSK) Jean-Pierre Garnier says the he does not foresee the US Food and Drug Administration (FDA) softening its position on drug approvals. More>>>

Avandia Heart Attack
-LawyersandSettlements.com
05/16/2008- New Orleans, LA: After being on Avandia for two years, Gail suffered a heart attack. When she was admitted to hospital, immediately following her heart attack, the doctors did an angiogram and found that all the arteries were blocked. Gail had to have five stents put in, which required two separate operations. More>>>

LegalView Reports on Details of FDA Warning to Avandia Manufacturer for Withholding
-TransWorldNews
05/05/2008- Denver, CO LegalView.com, the number one resource for everything legal on the Internet, published news of the most recent Avandia update specifying the U.S. Food and Drug Administration (FDA)'s warnings to GlaxoSmithKline, makers of the type 2 diabetes drug Avandia. The warning resulted from the manufacturer's noncompliance with reporting post-marketing research information on the drug. The company did not issue the full breadth of research for 10 ongoing clinical trials that spanned from 2001 to 2007. More>>>

Avandia One Year Later
-Lawyers and Settlements
05/04/2008- A new report suggests that doctors are continuing to be increasingly concerned with regard to the safety and efficacy of Avandia, with that concern increasing nine-fold since the once-popular GlaxoSmithKline diabetes drug blasted into the headlines last spring. More>>>

Concern From Doctors Regarding the Cardiovascular Safety of GlaxoSmithKline's Avandia Increases Nine-Fold Following Publication of Meta-Analysis

-PRNewswire

04/23/2008- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that the percentage of primary care physicians (PCPs) and endocrinologists who consider the cardiovascular safety of GlaxoSmithKline's Avandia to be a major concern increased more than nine-fold following publication of a meta-analysis. More>>>

FDA: Glaxo withheld Avandia studies
Bloomberg News
04/17/2008-GlaxoSmithKline PLC, Europe's largest drugmaker, failed to properly disclose studies of Avandia, the diabetes pill linked to potentially deadly side effects, U.S. regulators said. More>>>

Glaxo Angers the FDA

-Motley Fool

04/11/2008- Every large-cap pharma seems to have at least one marketed drug that produces endless streams of woe for them. In GlaxoSmithKline's (NYSE: GSK) case, the drug in question is its type 2 diabetes compound, Avandia. More>>>

GSK rebuked for missing Avandia reports

-Fierce Pharma

04/10/2008- GlaxoSmithKline got a trip to the FDA woodshed for failing to regularly report post-marketing data it was gathering on the diabetes med Avandia. GSK failed to include updates on as many as 18 different trials in its annual reports to the agency on that med. The agency rebuked GSK, ordering the company to get its act together pronto. More>>>

FDA: Glaxo holds studies on Avandia-
Foodconsumer.org

04/09/2008- GlaxoSmithKline Plc failed to report all the required studies on its diabetes drug Avandia to the Food and Drug Administration, the agency said in a warning letter released on Tuesday. More>>>

Glaxo Failed to Disclose Avandia Studies, FDA Says

-Bloomberg

04/08/2008- GlaxoSmithKline Plc, Europe's largest drugmaker, failed to properly disclose studies of the diabetes pill Avandia after it was linked to potentially deadly side effects, U.S. regulators said. More>>>

Doctors demand freeze on use of diabetes drug for heart patients
The Scottsman
SCOTTISH doctors have said there is "no defence" for the use of a widely prescribed diabetes drug after warnings that it should not be used in patients with heart problems, The Scotsman can reveal.The consultants, who work in the NHS Greater Glasgow and Clyde area, recommend no new patients are given Avandia – also known as rosiglitazone. More>>>

Avandia: Meant to Help but Killed Instead
Edmonton, AB:
03/30/2008- Early in August 2006, Vivian's mother went to the hospital in Edmonton to have some cancer tests done. However, when she arrived the doctors noticed that the left side of her body was swollen. They took her vital signs and noticed her heart was racing. She was admitted to hospital that day, and on further testing the doctors discovered that her heart was enlarged as well. Over the next few days the doctors were unable to bring Vivian's mother's heart rate under control and she died. More>>>

New Guidelines, Safety Issues Reshape
Diabetes Space
03/29/2008- The diabetes landscape is a tad riskier for drugs in development that have a safety glitch or two, and the bottom line could mean higher costs.
New FDA draft guidance calls for more patients and lengthier trials for companies with certain safety issues, but the rules are no different from what is expected in drug development for other chronic conditions, the agency has said. More>>>

Diabetics in limbo over conflicting blood sugar studies
-Forbes

03/16/2008 - Donald McEwen was driving on I-480 when he saw an ad on the back of a bus recruiting people for a study on diabetes. More>>>

FDA's review process under investigation

-Forbes

03/04/2008 - The government's watchdog agency is investigating whether the Food and Drug Administration's drug-review process cleared two blockbuster medications without sufficient proof of their safety or effectiveness. More>>>

FDA Ponders Stricter Rules For Diabetes Drugs
-Forbes
03/04/2008 - In the wake of the controversy over the diabetes drug Avandia, the U.S. Food and Drug Administration is considering tougher standards for how and when diabetes drugs will be tested for risks to the heart. More>>>

Consumers tune out FDA warnings
-CNN
02/25/2008 - A flood of drug safety warnings from the Food and Drug Administration may have physicians and patients suffocating from information saturation. Experts say there are too many red flags for them to pay attention.

"It seems that almost weekly we're getting a safety missive," said Les Funtleyder, an analyst who covers the pharmaceutical industry for trading firm Miller Tabak. "We're almost getting safety fatigue." More>>>

Medication Under a Microscope
-Washinton Post
02/19/2008 - A series of surprising findings about some of the most widely accepted assumptions in medicine has renewed debate about how aggressively doctors use drugs to prevent and treat some of the nation's
leading health problems. More>>>

Diabetes drug and conflicts of interest
-Science Daily
02/04/2008 - So much for confidential peer review.
Last May, a controversial paper in the New England Journal of Medicine (NEJM) reported that a popular diabetes drug—rosiglitazone, sold under the brand name Avandia—substantially hikes a user's risk of heart attack. More>>>

New England Journal reviewer tipped drug firm, Nature reports
- Boston Globe
01/31/2008 - A peer reviewer for the Waltham-based New England Journal of Medicine leaked a negative article about a diabetes drug to its manufacturer more that two weeks before the study appeared, another major scientific journal reports today. More>>>

Article on Avandia Study Was Leaked to Glaxo
- Wall Street Journal

01/31/2008 - Weeks before an influential article was published last year in the New England Journal of Medicine linking the diabetes drug Avandia to a risk of heart attacks, a physician helping peer-review the article broke the Journal's confidentiality rules and leaked a copy to the drug's maker, GlaxoSmithKline PLC. More>>>

Reviewer leaked Avandia study to drug firm
- Nature
01/30/2008 - A peer reviewer for The New England Journal of Medicine (NEJM ) broke confidentiality and leaked a damaging report about the blockbuster diabetes drug Avandia to the drug's manufacturer weeks ahead of publication, Nature has learned. More>>>

Avandia Study Results Were Leaked Early to Glaxo
- CNBC
01/30/2008 - The wall between a prestigious medical journal and a major drug company may have been shattered. More>>>

FDA Procedures Draw Scrutiny
- Wall Street Journal
01/25/2008 - Controversies about cholesterol drug Vytorin and diabetes drug Avandia are reigniting debate over what evidence the Food and Drug Administration requires to approve drugs -- and may generate pressure on the agency to raise its bar. More>>>

GlaxoSmithKline to revise labeling for Avandia after EU regulator's decision
- CNN
01/24/2008 - GlaxoSmithKline (NYSE:GSK) PLC said is to revise the labeling on its Avandia diabetes product to include additional warnings that the product may be associated with an increased risk of heart attacks, after a decision by the European regulator (CHMP) today. More>>>

Avandia, human genome among the things we've learned from in the past year

\- Mansfield News Journal
01/21/2008 - Every year the Harvard Health Letter chooses what it considers to be the top 10 health stories of the year. During 2007, there weren't many instant breakthroughs that would qualify as scientific discoveries. Instead, we saw a slow, steady accumulation of data from multiple studies and clinical trials that finally reached a critical mass that could be considered an important health story. More>>>

List of problem prescription drugs is growing
- NewsDay
01/21/2008 - An increasing number of prescription drugs - some that have been widely promoted through seductive advertising - are turning out to have problems long after they've reached the market. More>>>

Diabetes and the Drugs to Control It Could Shorten Your Life
-American Chronicle
01/17/2008 - I'm often asked, "How can I live to be 100 years old?" My answer is simple, "Just say no to prescription drugs and learn how to control insulin and blood sugar." More>>>

Doctors Say Avandia Warning Label Should Tout Vegan Diet
01/15/2008 - A professional doctors' group has petitioned the Food and Drug Administration to require that Avandia's warning label include a statement that a low-fat vegan diet is a safer, more effective approach to lowering blood sugar levels than the drug itself. More>>>

Government Estimates 83,000 Excess Heart Attacks Caused By Avandia dissident news
-dissident news
01/09/2008 - According to a November 2007 report by the Senate Finance Committee, an analysis by FDA scientists presented at a July 30, 2007, safety panel meeting estimates that Avandia has caused approximately 83,000 excess heart attacks since coming on the market. More>>>

Avandia study shows increased heart risks, death
-Asbury Park Press
01/08/2008 - Older patients who took Avandia had a higher risk of heart attacks, congestive heart failure and death than those on other diabetes pills, according to a study of nearly 160,000 Canadians. More>>>

Year in Health: Here's to your safety

-USA Today
12/23/2007 - Persistent questions about the safety of both prescription and over-the-counter drugs, a menacing microbe spreading throughout the U.S. and a globe-trotting TB patient garnered headlines this past year. A look back at the top health stories of 2007: More>>>

Thiazolidinediones May Cause Increased Cardiac Risk in Older Adults
-About.com
12/13/2007 - A study that appeared in the Journal of the American Medical Association (JAMA) on Dec. 12th, 2007, shows that people over 65 may have an increased risk of congestive heart failure and heart attack, compared to younger people, with the diabetes drugs rosiglitazone (Avandia) and pioglitazone (Actos) which are in the class of thiazolidinediones (TZD's). More>>>

Avandia Risks May Cost Glaxo $300 Million in Alzheimer's Sales
-Bloomberg
12/13/2007 - GlaxoSmithKline Plc is likely to delay marketing its troubled Avandia diabetes pill as an Alzheimer's disease treatment because patients are reluctant to volunteer for research studies. More>>>

New Study Questions Safety of Diabetes Drug
-CBS
12/13/2007 - A new study out of Canada has been added to those that question the safety of the diabetes drug Avandia. More>>>

New Avandia study reaffirms heart risk
-USA Today
12/12/2007 - Older patients who took Avandia had a higher risk of heart attacks, congestive heart failure and death than those on other diabetes pills, according to a study of nearly 160,000 Canadians out Wednesday. More>>>

Another Study Finds Heart Risks in a Diabetes Drug
-New York Times
12/12/2007 - An independent analysis of thousands of older people with diabetes found that those treated with the widely used drug Avandia had significantly elevated risks of heart attack and death. More>>>

Avandia risks highlighted
-Baltimore Sun
12/12/2007 - Canadian researchers furnished the strongest evidence to date linking the popular diabetes drug Avandia to an increased risk of heart attack in a scientific study released yesterday. More>>>

GlaxoSmithKline highlights flaws in new Avandia analysis-
PharmaTimes
12/12/2007 - It must feel like Groundhog Day for GlaxoSmithKline as another analysis has been revealed which claims that Avandia, as well as Takeda’s Actos, is associated with an increased risk of congestive heart failure, heart attack and death compared with other oral diabetes drugs in older patients. More>>>

Study: 2 diabetes drugs raise heart risks
- Chicago Tribune
12/12/2007 - Older diabetes patients treated with Takeda Pharmaceutical North American Inc.'s Actos and GlaxoSmithKline PLC's Avandia had a "significant" increased risk of heart attack, congestive heart failure and death compared with those taking a more established treatment, according to a study in this week's Journal of the American Medical Association. More>>>

Avandia, Actos Raise Heart Risks For Older Diabetes Patients
-Wall Street Journal
12/11/2007 - Older patients treated with diabetes drug Avandia, sold by GlaxoSmithKline PLC, and Actos, made by Takeda Pharmaceutical Co. Ltd., have a significantly increased risk of heart attack, congestive heart failure and death compared to the other diabetes treatments, according to an article published Tuesday in the Journal of the American Medical Association. More>>>

Canadian study finds heart risks with Avandia
-CTV
12/11/2007 - The popular diabetes medication Avandia is under scrutiny again. A new Canadian study finds that the drug, along with others like it, increases the risk of heart failure, heart attacks and death in older adults. More>>>

Glaxo's Avandia, Takeda's Actos Increase Heart Risks, JAMA Says
-Bloomberg
12/11/2007 - Older people taking GlaxoSmithKline Plc's Avandia and Takeda Pharmaceutical Co.'s Actos had a higher risk of heart attacks, failure and death than those taking other diabetes pills, a study by Canadian researchers showed. More>>>

Glaxo diabetes drug raises heart risk in study
-Reuters
12/11/2007 - Another study has found evidence that certain diabetes drugs, especially GlaxoSmithKline's Avandia, can cause heart attacks and death, but the company said the findings did not make scientific sense. More>>>

GSK disappointed as two PBMs remove Avandia from formulary
- PharmaTimes
12/07/2007 - GlaxoSmithKline’s controversial type 2 diabetes drug Avandia is back in the headlines following the news that two major pharmacy benefit managers in the USA are pulling the treatment from their formularies. More>>>

Stronger heart attack warning for Avandia
-NZ.doctor.co.nz
12/5/2007 - Prescribing information about the diabetes drug rosi-glitazone (Avandia) is being updated to include a stronger warning about the risk of heart attack. More>>>

If you or a loved one have experienced an Avandia heart attack, or Avandia stroke, Avandia congestive heart failure, Avandia cardiovascular disease or if you have lost a loved one to an Avandia death you may be entitled to compensation. Contact the Avandia attorneys of Ennis & Ennis today for a free confidential case evaluation. Our on staff nurse and lawyers are standing by to answer any questions you may have regarding Avandia's side effects, a possible Avandia class action lawsuit, or any other type of Avandia litigation.